How to calculate Blood Alcohol Content problems using Algebra
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Here’s a quick overview of the pros and cons of mixing doxycycline and alcohol. Learn about the dangers and potential consequences and discover why Doxycycline is the only antibiotic with this unique factor. Doxycycline does share some common side effects with alcohol and we have additional at: Visit https://www.addict-help.com/doxycycline-and-alcohol/

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A study found that most people believe that mixing antibiotics with alcohol will either stop the medication working or make you sick. But what really happens?

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Here is a step-by-step video on how to register your company with FMCSA Clearinghouse.

I go over the clearinghouse registration portal and the FMCS portal. You have to log into your FMCSA Web Portal first and authorize yourself as the Clearinghouse contact rep.

It’s just a few extra steps but I go over the entire process here.

FMCSA Clearinghouse registration: https://clearinghouse.fmcsa.dot.gov/
FMCSA web portal: https://portal.fmcsa.dot.gov/login
_____________
For New MC#!
You will have a new entrant audit within the first 12 months of operating. Mandated by FMCSA.

You can learn more on our website and download our free checklist to be prepared.
👉USDOT New Entrant Audit Checklist:
✅https://www.truckersauthority.com/new-entrant-audit-checklist

Need a Trucking Insurance Quote For Your Authority?
Give our friends at Gold River Brokerage a call!
Speak to a trained USDOT, Licensed Transporation Insurance professional.
👉Call For A Quote Today: (702) 660-9769
👉https://goldriverinsurance.com/trucking/quotes/

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Looking for an ELD company?
Check out Motive ELD,
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They offer more than just ELD, check them out: https://mbsy.co/3qJ7GL

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USDOT & MC Number is not the only part of the process.

These are the most common permits/steps you need to complete your trucking permits.

✅Business Setup (Corporation or Sole Proprietor)
✅USDOT Number
✅Motor Carrier Number
✅BOC-3
✅UCR
✅Drug and Alcohol Consortium Program
✅State Permit
✅Apportioned Registration
✅IFTA Registration

Additional Permits:
✅SCAC Code
✅KYHUT
✅Oregon Weight Permit
✅NM Weight Permit
✅KYU Weight Permit
✅CA Number
✅MCP
✅TXDMV Number

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(USMLE topics) Alcoholic fatty liver, alcoholic hepatitis, and cirrhosis: Signs and symptoms, risk factors, pathophysiology, complications, diagnosis and treatment.
This video is available for instant download licensing here: https://www.alilamedicalmedia.com/-/galleries/all-animations/digestive-system-videos/-/medias/012159d6-87f0-425d-bd0d-37b284ff287a-alcoholic-liver-disease-narrated-animation
©Alila Medical Media. All rights reserved.
Voice by : Marty Henne
Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia
All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Alcoholic liver disease is liver damage caused by alcohol abuse. The risk of developing liver disease correlates with the amount and duration of alcohol use. Daily drinking poses a higher risk than binge drinking. Other risk factors include gender, genetics, and obesity.
Alcoholic liver disease includes 3 disorders that develop in sequence: alcoholic fatty liver, alcoholic hepatitis, and cirrhosis.
Alcoholic fatty liver is accumulation of liver fat as a result of alcohol use. The liver is usually enlarged but not tender. There are often no symptoms and the condition can be reversed if the patient stops drinking.
Alcoholic hepatitis is liver inflammation. Symptoms can range from mild to severe and may include fever, jaundice, fatigue, and a tender, painful and enlarged liver.
Cirrhosis is when a large amount of hepatic tissue is permanently replaced with non-functional scar tissue, known as fibrosis. Symptoms range from those of alcoholic hepatitis to those of end-stage liver disease. The liver eventually shrinks. Cirrhosis cannot be reversed.
The liver is the major site of alcohol metabolism. Two main pathways are involved: alcohol dehydrogenase, ADH; and cytochrome P-450 2E1, or CYP-2E1.
ADH converts alcohol to acetaldehyde. A second enzyme, acetaldehyde dehydrogenase, ALDH, then metabolizes acetaldehyde to acetate. People who have low levels of ALDH are more susceptible to toxic effects of acetaldehyde. Both of these reactions convert NAD+ to NADH. An increased NADH/NAD+ ratio promotes fatty liver by inhibiting fatty acid oxidation and stimulating fatty acid synthesis.
In addition, acetaldehyde also promotes production of enzymes involved in fatty acid synthesis, and inhibits expression of enzymes implicated in fat oxidation. Alcohol use has also been shown to reduce export of fat from the liver. All these events lead to fat accumulation in hepatic cells.
Chronic alcohol use upregulates the CYP-2E1 pathway. This pathway generates harmful reactive oxygen species, which can damage proteins and DNA. The effect is exaggerated in patients who are deficient in antioxidants due to malnutrition. Chronic alcohol exposure also activates hepatic macrophages, triggering inflammation. In addition, acetaldehyde can bind to cellular proteins, forming so-called adducts that are seen as foreign antigens by the immune system, provoking the body’s inflammatory attacks.
Chronic inflammation and subsequent attempts at tissue repair lead to formation of scar tissue. As a result, the liver internal structure is disrupted, impairing its functions. Scarring of liver tissue also obstructs blood flow, causing high blood pressure in the portal vein that brings blood from the intestine to the liver.
As liver functions decline, toxins that are normally removed by the liver can now reach the general circulation and pass into the brain, producing symptoms such as confusion, drowsiness, tremor, or even coma, in a condition known as hepatic encephalopathy. Portal hypertension may cause variceal bleeding, enlarged spleen, and abdominal distension.
Diagnosis is usually based on signs of liver dysfunction, other symptoms related to alcohol use, history of heavy drinking, liver function tests and complete blood count.
Abstinence is the best treatment. Supportive care includes good nutrition and vitamin supplements. Corticosteroids may be used to reduce inflammation but their effectiveness is till debatable. Liver transplantation may be considered for abstinent patients with severe liver damage.
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The dangers of regular excessive drinking go way beyond the morning hangover. Those who drink heavily run the risk of damaged brain tissue, an array of liver disease and a variety of cancers. Keep these risks in mind when asking if you’re good for one more.

Produced by Rob Ludacer. Original Reporting by Kevin Loria and Will Wei.

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Want to know how much alcohol to serve to your guests? Here is the one stop shop to breakdown exactly how much alcohol to buy. This all inclusive list comes complete with a cheat sheet!

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The NHS could save £27m a year by changing the way it deals with alcoholic patients, new research seen by the Victoria Derbyshire programme suggests. Alcohol abuse costs the NHS £3.8bn a year, £145 for each household in the UK – one in three of all A&E admissions are alcohol related, which can rise to 70% on a weekend. But patients who attend the emergency department or inpatient ward at a Manchester hospital in with issues related to alcohol abuse can now be sent to a specialist unit where they are treated for their addiction for a week. Some 75% of the people who come through the unit do not go back to hospital for at least the next three months. Independent analysis from John Moore’s University found the unit saved the NHS £1.3m a year. If the same approach was taken across the country the researchers say it could save the NHS £27.5 m in England alone.
Jim Reed reports.

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Rich Gang feat. Young Thug & Rich Homie Quan – Lifestyle

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